The 1 Column layout can be used to create a dramatic home page with a large image or focal point. It is also a good choice for a landing page, or any other page that has a combination of text, images, and video.
Two columns with left bar
The 2 Columns with Left Bar layout is often used for pages with navigation on the left, such as a catalog or search results pages with layered navigation. It is also an excellent choice for home pages that need additional navigation or blocks of supporting content on the left.
Two columns with right bar
With a 2 Columns with Right Bar layout, the main content area is large enough for an eye-catching image or banner. This layout is also often used for Product pages with blocks of supporting content on the right.
The 3 Column layout has a center column that is wide enough for the main text of the page, with room on each side for additional navigation and blocks of supporting content.
The Empty layout can be used to define custom page layouts. To learn more, see the Designer’s Guide to Magento.